Dehydrocostus Lactone

CAS No. 477-43-0

Dehydrocostus Lactone ( Dehydrocostus Lactone; (-)-Dehydrocostus lactone. )

Catalog No. M18596 CAS No. 477-43-0

Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 58 In Stock
25MG 115 In Stock
50MG 192 In Stock
100MG 295 In Stock
500MG 710 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dehydrocostus Lactone
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.
  • Description
    Dehydrocostus Lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ. Dehydrocostus Lactone Suppresses Proliferation of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl-JAK/STAT Signaling Pathways. Dehydrocostus Lactone Inhibits Proliferation, Antiapoptosis, and Invasion of Cervical Cancer Cells Through PI3K/Akt Signaling Pathway.
  • Synonyms
    Dehydrocostus Lactone; (-)-Dehydrocostus lactone.
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    477-43-0
  • Formula Weight
    230.3
  • Molecular Formula
    C15H18O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 62.5 mg/mL; 271.39 mM
  • SMILES
    C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C
  • Chemical Name
    (3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dong GZ, et al. PhytOthers Res. 2015 May;29(5):680-6.
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